This study aims to identify how the news about coronavirus is affecting people, whether people are having to isolate, and their experiences of isolating. It aims to inform understanding about the effects of social isolation measures on people’s mental health. The findings will be used to help develop ways to support people psychologically and socially during this outbreak.
Participation is open to people over the age of 18 living in the UK and is entirely voluntary. You do not have to be in isolation to take part.
You will be asked to complete one survey now and then a shorter survey once a week whilst this pandemic continues and social isolation measures are in place. You can opt out of taking part in future surveys at any point by simply ignoring the follow-up invitation.
To find out more, and to take part in this study, please follow this link.
NorAD – This study is currently on hold due to Covid-19.
Currently approved drugs for Alzheimer’s Disease, (the most common cause of dementia), have a very small effect on thinking and quality of life, and most work by increasing levels of acetylcholine, the neurotransmitter most closely linked with memory.
However there is also clear evidence of dysfunction of the noradrenaline system, which appears to play a particularly important role in general arousal and attention, which are affected soon after memory in Alzheimer’s Disease.
This trial will look at whether boosting noradrenaline, in addition to standard treatment, will improve attention and more general aspects of thinking in patients with Alzheimer’s Disease.
What happens in the study?
This trial is a randomised controlled trial which means that half the participants will receive a drug called Guanfacine, which has been shown to boost attention and memory in animal studies and in healthy humans, and is licensed for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and half will be given a placebo (a drug which has no effect on the person taking it).
This will help assess whether boosting noradrenaline, in addition to standard treatment, will improve attention and more general aspects of thinking in patients with Alzheimer’s Disease.
Mental Health Studies
Sleep and psychotic features – This study is currently on hold due to Covid-19.
People who suffer from mental health disorders often have difficulties regulating their mood and emotions. They are also often troubled with disrupted sleeping patterns which can range from being unable to fall asleep, sleeping at the wrong time of day, or having excessive sleepiness.
Poor sleep also predicts a ‘relapse’ or sudden worsening of symptoms. We are interested in finding out whether there is an association between the difficulty of regulating mood and of sleep patterns.
This study has been designed to investigate the relationship between sleep and mood in people who have been referred to NHS mental health services, to understand if sleep problems are present in these people.